Stowe’s landmark novel, Uncle Tom’s Cabin, has often been cited as one of the causes of the Civil War. She became outraged by written accounts of the injustice and cruelty of the slave system and traveled to the South to investigate it herself. The material she gathered became the source for Uncle Tom’s Cabin; or Life Among the Lowly. The book, which was first published in 1831 in serial form in an abolitionist newspaper, became an immediate sensation, soon gaining worldwide popularity. Stowe was also an ardent supporter of women’s rights, and she collaborated with her sister, Catherine Beecher, on nineteen domestic-science books.